ZHNAG Junchuan, CAO Xiangling, WU Xingui,ZHOU Lifang,LIU Jianwei

（1Department of Traditional Chinese Medicine,the Fiest Affiliated Hospital of Guangxi Medical University, Nanning 530021,China）

Abstract: Objective: To observe the effects of electroacupuncture at Quchi（LI11）  and Zusanli（ST36）on  motor  function  and  Nissl  of  cortex  neurons  in  rats  with  unilateral  focal  cerebral infarction, and to explore its relationship with the recovery of motor function in rats.Methods: 60 male SD rats were randomly divided into the sham operation group (n=6) and the operation group (n=54).The operation group were under the operation of the right middle cerebral artery occlusion (MCAO) by the modified Longa’   methods, and 48 qualified rats were randomly divided into the model group(n=24),and the electroacupuncture group(n=24).All subgroups were sacrificed at 6 rats  when  3  days,7  days,14  days,28  days  after  the  operation.The  electro-acupuncture  group received electroacupuncture at Quchi（LI11）and Zusanli（ST36）for  28  days.  The neurological function and foot error test were examined at 1st , 3st, 7st, 14st, 28st day on all rats and  detectedthe  changes  of  the  histopathology  of  injury  by  hematoxylin-eosin  and  Nissl staining.Results:Compared  with  the  model  group,  the  neurological  deficit  score  in electroacupuncture  groups  were  no  diffiences  after  1d  and  3d(p>0.05).But  both  the  scores  of neurological  function  and  root  error  test  of  rats  in  electroacupuncture  groups  were lower(p<0.05).Result from HE and nissl  observation  show that the damage neurons in group the acupuncture  are  lighter  than  non-acupuncture  group  at  3stday,and  the  nissl  bodies  begin  to increasing  at  14stday.there  are  significantly  improve  than  non-acupuncture  group  at  3st  and 28stday.Conclusion:  Electroacupuncture  not only  increase the number of nissl bodies to protect the  damaged  nerve  cells,  but  also  maintain  its  steady  cells’strusture,  thus  promoting  the  focal cerebral infarction, the recovery of motor function of rat.

Key words: Electric acupuncture;Li 11;Focal cerebral infarction;Nissl body