The application of the Animal Energy Metabolism Monitoring System (AEMMS) in the interventions of acute alcoholic liver injury by acupuncture
LI Shunyue,SONG Xiaojing,WANG Shuyou,ZHANG Dong
(1.Institute of Acupuncture and Moxibustion, Chinese Academy of Chinese Medical Sciences, Beijing 100070)
Abstract: Objective: To explore the value of using the animal energy metabolism monitoring system (AEMMS) in the study to improve the energy metabolism of acute alcohol liver injury in rat by acupuncture. Methods: 30 rats were divided into control group, model group and EA group randomly. Model group and EA group were gavaged with 50% ethanol (12ml / kg), which were resulting in an animal model of acute alcoholic liver injury. EA group after gavaged was treated 30min each time every day by acupuncture Zusanli(ST -36), and the treatment continued 3 days. To observe the RER, heat, feeding and drinking continuously for 96h in each group at same time by AEMMS. Results: The RER，feeding and drinkingdecreased significantly in rats with ALI，the heat in which increased；There was an increased tendency of the RER, feeding and drinking，and an declined tendency of the heat in model rats by EA intervention. Conclusion: It was indicated that there was a practical value of AEMMS through the study of the energy metabolism of rats with ALI by acupuncture.
Key words: Acupuncture and moxibustion, Liver injury, energy metabolism