Different intensity of acupoints sticking therapy moderately severe persistent allergic rhinitis: a randomized controlled study
HU Qimiao, GUPengPeng, JIANG Xia, JIANG Fangqi, ZHUANGJinfei, ZHENG Haisong ,Y ANG Guanhu,JIANG Son ghe
(1. The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University,Zhejiang,Wenzhou 325027;2. Integrative & Optimized Medicine Research center, China-USA Institute for Acupuncture and Rehabilitation of Wenzhou Medical University, Wenzhou 325000)
Abstract: Objective: To observe and compare the sanfu days of different intensity of acupoint sticking with moderately severe persistent allergic rhinitis the clinical curative effect and security. Methods: 160 patients with moderately severe persistent allergic rhinitis were randomly divided into treatment group 1 (40 cases), treatment group 2 (40 cases) and treatment groups 3 (40 cases) and the placebo group (40 cases).Unified use compound white mustard prescription (white mustard, angelica dahurica, asarum, corydalis yanhusuo). Treatment group 1 with ginger juice to reconcile the traditional Chinese medicine powder (namely "ginger attach"), 2 and 3 treatment groups mixed with honey powder (namely "honey sticking"), the placebo group made from millet powder, and distilled water appearance the same fake ointment. Treatment group 1 and 2 treat 2h, Treatment group 3 and 4 treat 6h, to attach 1 times a week during the sanfu days, attach five weeks in a row. The acupoints of the observation group were mainly in the GV. Observe four groups before and after five weeks of treatment in patients with nasal symptom scores (TNSS), nasal mucous membrane inflammation in the quality of life questionnaire (RQLQ), blood eosinophils (EOS), relative and compare the clinical curative effect of two groups. In addition, the observed treatment groups incidence of adverse reactions of the skin. Result: (1) treatment after treatment group were lower before the treatment (P< 0.05, P < 0.01), the improvement of the three treatment groups of TNSS degree is better than that of treatment 1 group, 2 group (P < 0.05).(2) patients in treatment group after treatment RQLQ total scores were lower (P < 0.05, P < 0.01), compared with treatment 1 group, 2 group, treatment group 3 RQLQ larger decreased (P< 0.05). (3) in treatment group after treatment EOS than before treatment were decreased (P < 0.05), there was no statistically significant difference between the treatment way (P > 0.05).(4) treatment group total effective rate was 76.3% (29/38) 1, 2 treatment group total effective rate was 71.8% (28/39), treatment group total effective rate was 85.0% (34/40), 3 is better than that of treatment 1 group, 2 group and the placebo group (P< 0.05, P< 0.01), the placebo group the total effective rate was 5.0% (2/40).Incidence of adverse reactions to skin group 1 was 39.5% (15/38), group 2 was 0.0% (0/39), treatment group 2.5% (1/40), 3 way difference between statistical significance (P < 0.05).Conclusion: different acupoints sticking strength can improve moderately severe persistent allergic rhinitis symptoms and quality of life. "Ginger attach" stimulus intensity big, 2 h after applied to the skin blisters; "Honey tone attach" stimulus is moderate, not a blister.6 h "honey sticking" mild skin irritation, in this study, the curative effect is strongest.
KEY WORDS: allergic rhinitis,persistent; acupoint-application; total nasal symptom score(TNSS);rhinoconjunctivitis quality of life questionnaire(RQLQ);randomized controlled trial (RCT)