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The application of the Animal Energy Metabolism Monitoring System (AEMMS) in the interventions of acute alcoholic liver injury by acupuncture

2018/05/02 14:59
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<p style="text-align: center;">LI Shunyue,SONG Xiaojing,WANG Shuyou,ZHANG Dong</p><p style="text-align: center;">(1.Institute of Acupuncture and Moxibustion, Chinese Academy of Chinese Medical Sciences, Beijing 100070)</p><p style="text-align: justify;"><strong>Abstract</strong>:&nbsp; <strong>Objective</strong>:&nbsp; To&nbsp; explore&nbsp; the&nbsp; value&nbsp; of&nbsp; using&nbsp; the&nbsp; animal&nbsp; energy&nbsp; metabolism&nbsp; monitoring&nbsp; system (AEMMS) in the study to improve&nbsp; the energy metabolism of&nbsp; acute alcohol liver injury in rat by acupuncture.&nbsp;<strong>Methods</strong>: 30 rats were divided into control group, model group and EA group randomly. Model group and EA group were&nbsp; gavaged&nbsp; with 50% ethanol (12ml / kg), which were resulting in an animal model of acute alcoholic&nbsp; liver&nbsp; injury.&nbsp; EA&nbsp; group&nbsp; after&nbsp; gavaged&nbsp; was&nbsp; treated&nbsp; 30min&nbsp; each&nbsp; time&nbsp; every&nbsp; day&nbsp; by&nbsp; acupuncture Zusanli(ST -36),&nbsp; and&nbsp; the&nbsp; treatment&nbsp; continued&nbsp; 3&nbsp; days.&nbsp; To&nbsp; observe&nbsp; the&nbsp; RER,&nbsp; heat,&nbsp; feeding&nbsp; and&nbsp; drinking continuously&nbsp; for&nbsp; 96h&nbsp; in&nbsp; each&nbsp; group&nbsp; at&nbsp; same&nbsp; time&nbsp; by&nbsp; AEMMS.&nbsp; Results:&nbsp; The&nbsp; RER,feeding&nbsp; and&nbsp; drinkingdecreased significantly in rats with ALI,the heat in which increased;There was an increased tendency of the&nbsp; RER, feeding and drinking,and an declined tendency of the heat in model rats by EA intervention.&nbsp;<strong> Conclusion</strong>:&nbsp; It was&nbsp; indicated&nbsp; that&nbsp; there was a&nbsp; practical value&nbsp; of AEMMS through the study of the energy metabolism of rats with ALI by acupuncture.&nbsp;</p><p style="text-align: justify;"><strong>Key words</strong>: Acupuncture and moxibustion, Liver injury, energy metabolism</p><p><br/></p>